Heterozygosity in an Isolated Population of a Large Mammal Founded by Four Individuals Is Predicted by an Individual-Based Genetic Model

Authored by Jaana Kekkonen, Mikael Wikstrom, Jon E Brommer

Date Published: 2012

DOI: 10.1371/journal.pone.0043482

Sponsors: No sponsors listed

Platforms: MATLAB

Model Documentation: Other Narrative Mathematical description

Model Code URLs: http://journals.plos.org/plosone/article/file?type=supplementary&id=info:doi/10.1371/journal.pone.0043482.s006

Abstract

Background: Within-population genetic diversity is expected to be dramatically reduced if a population is founded by a low number of individuals. Three females and one male white-tailed deer Odocoileus virginianus, a North American species, were successfully introduced in Finland in 1934 and the population has since been growing rapidly, but remained in complete isolation from other populations. Methodology/Principal Findings: Based on 14 microsatellite loci, the expected heterozygosity H was 0.692 with a mean allelic richness (AR) of 5.36, which was significantly lower than what was found in Oklahoma, U. S. A. (H = 0.742; AR = 9.07), demonstrating that a bottleneck occurred. Observed H was in line with predictions from an individual-based model where the genealogy of the males and females in the population were tracked and the population's demography was included. Conclusion: Our findings provide a rare within-population empirical test of the founder effect and suggest that founding a population by a small number of individuals need not have a dramatic impact on heterozygosity in an iteroparous species.

Tags

Diversity cattle Consequences Size Dna White-tailed deer Decline Bovine microsatellites Markers Bottlenecks