Contact inhibition of growth described using a multiphase model and an individual cell based model

Authored by J Galle, L Preziosi, A Tosin

Date Published: 2009

DOI: 10.1016/j.aml.2008.06.051

Sponsors: European Union

Platforms: No platforms listed

Model Documentation: Other Narrative Mathematical description

Model Code URLs: Model code not found

Abstract

In this work the phenomenon of contact inhibition of growth is studied by applying an individual based model and a continuum multiphase model to describe cell colony growth in vitro. The impact of different cell behavior in response to mechanical cues is investigated. The work aims at comparing the results from both models from the qualitative and, whenever possible, also the quantitative point of view. Crown Copyright (C) 2009 Published by Elsevier Ltd. All rights reserved.

Tags

proliferation Populations In-vitro Mathematical-model Tumor invasion