MODELS, MEASUREMENT AND INFERENCE IN EPITHELIAL TISSUE DYNAMICS
Authored by Philip K Maini, Alexander G Fletcher, Oliver J Maclaren, Helen M Byrne
Date Published: 2015
DOI: 10.3934/mbe.2015.12.1321
Sponsors:
United Kingdom Engineering and Physical Sciences Research Council (EPSRC)
Platforms:
No platforms listed
Model Documentation:
Other Narrative
Mathematical description
Model Code URLs:
Model code not found
Abstract
The majority of solid tumours arise in epithelia and therefore much
research effort has gone into investigating the growth, renewal and
regulation of these tissues. Here we review different mathematical and
computational approaches that have been used to model epithelia. We
compare different models and describe future challenges that need to be
overcome in order to fully exploit new data which present, for the first
time, the real possibility for detailed model validation and comparison.
Tags
cancer
Tumor-growth
Colonic crypt
Rearranging disordered patterns
Multistage cell lineages
Extended
potts-model
Dissociated cells
Monoclonal
conversion
Population kinetics
Inverse problems