The Importance of Being Hybrid for Spatial Epidemic Models: A Multi-Scale Approach

Authored by Arnaud Banos, Nathalie Corson, Benoit Gaudou, Vincent Laperriere, Sebastien Rey Coyrehourcq

Date Published: 2015

DOI: 10.3390/systems3040309

Sponsors: No sponsors listed

Platforms: NetLogo

Model Documentation: Other Narrative Mathematical description

Model Code URLs: Model code not found

Abstract

This work addresses the spread of a disease within an urban system, defined as a network of interconnected cities. The first step consists of comparing two different approaches: a macroscopic one, based on a system of coupled Ordinary Differential Equations (ODE) Susceptible-Infected-Recovered (SIR) systems exploiting populations on nodes and flows on edges (so-called metapopulational model), and a hybrid one, coupling ODE SIR systems on nodes and agents traveling on edges. Under homogeneous conditions (mean field approximation), this comparison leads to similar results on the outputs on which we focus (the maximum intensity of the epidemic, its duration and the time of the epidemic peak). However, when it comes to setting up epidemic control strategies, results rapidly diverge between the two approaches, and it appears that the full macroscopic model is not completely adapted to these questions. In this paper, we focus on some control strategies, which are quarantine, avoidance and risk culture, to explore the differences, advantages and disadvantages of the two models and discuss the importance of being hybrid when modeling and simulating epidemic spread at the level of a whole urban system.

Tags

Coupled chemical-reactions