Constructing a new individual-based model of phosphine resistance in lesser grain borer (Rhyzopertha dominica): do we need to include two loci rather than one?
Authored by Michael Renton, Mingren Shi, James Ridsdill-Smith, Patrick J Collins
Date Published: 2012
DOI: 10.1007/s10340-012-0421-6
Sponsors:
Australian Government
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Abstract
In this article, we describe and compare two individual-based models
constructed to investigate how genetic factors influence the development
of phosphine resistance in lesser grain borer (R. dominica). One model
is based on the simplifying assumption that resistance is conferred by
alleles at a single locus, while the other is based on the more
realistic assumption that resistance is conferred by alleles at two
separate loci. We simulated the population dynamic of R. dominica in the
absence of phosphine fumigation, and under high and low dose phosphine
treatments, and found important differences between the predictions of
the two models in all three cases. In the absence of fumigation, starting from the same initial frequencies of genotypes, the two models
tended to different stable frequencies, although both reached
Hardy-Weinberg equilibrium. The one-locus model exaggerated the
equilibrium proportion of strongly resistant beetles by 3.6 times, compared to the aggregated predictions of the two-locus model. Under a
low dose treatment the one-locus model overestimated the proportion of
strongly resistant individuals within the population and underestimated
the total population numbers compared to the two-locus model. These
results show the importance of basing resistance evolution models on
realistic genetics and that using oversimplified one-locus models to
develop pest control strategies runs the risk of not correctly
identifying tactics to minimise the incidence of pest infestation.
Tags
Simulation
Evolution
Management
Storage
Coleoptera
Insect populations